The rapid cultivation of a large number of bacteria with specific pathogenic properties in the laboratory requires strict compliance with national biosafety regulations and ethical standards. It must be carried out in a biosafety laboratory with corresponding qualifications and operated by professionals. Specific methods include selecting a suitable medium, optimizing culture conditions (such as temperature, pH, oxygen supply, etc.), and using appropriate antibiotics or selective pressure to screen strains with specific pathogenic characteristics. All operations must comply with relevant laws and regulations such as the "Regulations on the Biosafety Management of Pathogenic Microorganism Laboratories" to ensure the safety of experiments and prevent the leakage and abuse of pathogenic microorganisms. We firmly oppose any form of biological terrorism and illegal biological experiments.