As of 2023, new synthetic drugs (New Psychoactive Substances, NPS) are constantly emerging worldwide, with a wide variety, and their chemical structure and pharmacological effects are constantly changing. The following are some of the new types of synthetic drugs and specific substances that have become more popular in recent years： ### 1. **Synthetic Cannabinoids (Synthetic Cannabinoids)** -**Common names**: Spice, K2, Black Mamba, Cloud 9 -**Features**: These substances simulate the active ingredient THC in cannabis, but the effect is stronger and unpredictable, and may cause serious health problems such as insanity, heart attack, and kidney failure. ### 2. **Synthetic Cathinones (Synthetic Cathinones)** -**Common names**: Bath Salts, Flakka, MDPV, α-PVP -**Features**: These substances simulate the effects of amphetamines and cocaine, but may cause extreme excitement, hallucinations, violent behavior and serious physical damage. ### 3. **Phenethylamines (Phenethylamines)** -**Common names**: 2C-B, 2C-I, NBOMe series (such as 25I-NBOMe) -**Features**: These substances have strong hallucinogenic effects and may cause serious psychological and physiological reactions, including anxiety, panic, and heart problems. ### 4. **Opiate Analogues (Opiate Analogues)** -**Common names**: Fentanyl (Fentanyl), Carfentanil (Carfentanil), U-47700 -**Features**: These substances are more effective than traditional opiate drugs (such as heroin) and can easily lead to overdose and death. ### 5. **Benzodiazepine Analogues (Benzodiazepine Analogues)** -**Common names**: Etizolam, Clonazolam, Flubromazolam -**Features**: These substances have powerful sedative and anxiolytic effects, but may cause severe dependence and withdrawal symptoms. ### 6. **Tryptamines (Tryptamines)** -**Common names**: DMT, 5-MeO-DMT, 4-AcO-DMT -**Features**: These substances have a strong hallucinogenic effect and may cause a profound spiritual experience, but they may also cause serious psychological reactions. ### 7. **Piperazines (Piperazines)** -**Common names**: BZP, TFMPP -**Features**: These substances have excitatory and hallucinogenic effects, which may cause cardiovascular problems and insanity. ### 8. **Other new synthetic drugs** -**Common names**: γ-hydroxybutyric acid (GHB), γ-butyrolactone (GBL), 1,4-butanediol (1,4-BD) -**Features**: These substances have sedative and hallucinogenic effects and are often used in sexual assault and are called "rape drugs”" ### 9. **Amphetamine Analogues (Amphetamine Analogues)** -**Common names**: 4-FA, 4-MA, Methamphetamine analogues -**Features**: These substances have a strong excitatory effect and may cause serious cardiovascular and mental problems. ### 10. **Other new substances** -**Common names**: Kratom, Salvia divinatum -**Features**: These substances have unique pharmacological effects and may cause different physiological and psychological reactions. ### Precautions： -**Unpredictability**: The chemical structure and mechanism of action of new synthetic drugs are often unknown, so their effects and side effects are difficult to predict. -**Legal risks**: Many new synthetic drugs have not yet been included in the scope of legal control, but their production and sales may still be illegal. -**Health risks**: The use of new synthetic drugs may cause serious health problems, including psychological and physical damage, and even death. ### Summary： The epidemic trend of new synthetic drugs is constantly changing, and their types and forms are constantly evolving. The public should be vigilant and avoid contact with and use of these substances so as not to cause serious harm to their own health and social safety. If you or someone you know is experiencing drug-related problems, it is recommended to seek professional help as soon as possible.